Below is a list of clinical trials and scientific research into the use of Vagus Nerve Stimulation and Sound Therapy in the treatment of Tinnitus. 





Helsinki Ear Institute study showing that tVNS can effectively be used to treat Tinnitus if paired with tailored sound therapy.


The Sixth International Conference on Tinnitus referencing tVNS and Combined  Sound therapy as a viable method for treating Tinnitus


‘How to Stop tinnitus by buzzing the vagus’


An observed reversal of the pathological neural activity observed in tinnitus, through VNS and sound therapy 


Medical Science College of China and Yichang TCM Hospital study, showing the positive effects of tVNS treatment when used in conjunction with sound therapy


tVNS can interfere with tinnitus related neural activity patterns, such as cortical gamma rhythms, causing reductions in tinnitus.


German study illustrating the therapeutic effects of tVNS for the treatment of chronic tinnitus


Non-invasive VNS can reduce sympathetic nerve activity (Fight or flight response, linked with negative association in Tinnitus)


Mood Enhancement and deactivation of the limbic system through tVNS


Non-invasive stimulation of the Vagus Nerve has effects consistent with that of ‘Classical’ Invasive stimulation through implanted electrodes.




Only minor and often resolvable side effects of treatment seen from over 10,000 patients over a 12 year period. Note: this paper is referring to invasive VNS (Implanted electrode)


No Major Contraindications were found with the treatment of Tinnitus through tVNS

VNS paired with tones excluding the tinnitus-matched frequency is safe and feasible. It seems to exert a beneficial effect in non-medication-taking patients, both with regard to the perceived sound and the distress.


tVNS device can safely and easily be applied to patients for clinical application


The method of tVNS and device are both feasible and appropriate for accessing cerebral vagus  nerve structures


tVNS does not appear to impact pupillary light reflex


fMRI study on non-invasive tVNS


Additional Benefits of tVNS


Overview of the clinical applications of Vagus Nerve Stimulation


The Vagus (Latin for Wanderer) nerve is linked to many parts of the body and stimulation could be beneficial in many other conditions, including heart failure, tinnitus, Depression, chronic hiccups, Alzheimer's disease and inflammatory diseases


Vagus nerve stimulation can efficiently modulate pain processing through nociception


tVNS for the treatment of drug resistant epilepsy

Parasym Health